This study found that about 88% of the US population would accept the COVID-19 vaccine but 14% indicated they would get vaccinated only if compensated.

It is estimated that payments of at least US$525 are needed to sufficiently incentivize 50% or more of those willing to get vaccinated only if compensated.

As vaccine efficacy levels were also found to affect vaccine demand, vaccines with relatively lower efficacy levels may result in higher vaccine hesitancy.