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Knockdown of HMGB1 attenuates LPS-induced podocyte injury. (a) Representative Western blotting analysis of HMGB1 expression in podocytes after HMGB1 siRNA transfection. (b) Representative Western blotting analysis image of supernatant HMGB1 and active caspase-3 expression in podocytes transfected by HMGB1 siRNA after exposure to LPS for 24 h. ∗P < 0.05 compared with the control group; #P < 0.05 compared with HMGB1 group; §P < 0.05 compared with the scramble group.
