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. 2021 Sep 27;2021:5245197. doi: 10.1155/2021/5245197

Figure 6.

Figure 6

Probiotic V and Met alone or in combination prevents ethanol-mediated oxidative stress and endoplasmic reticulum (ER) stress in the male Wistar rat model. mRNA expression of (a) CYP2E1, (b) NOX and ER stress gene (c) CHOP, and (d) Grp78 in the male Wistar rat colon. The gene expression levels were measured after normalizing against 18S. Values are expressed as mean ± SD of six rats. Statistical analysis: one-way ANOVA followed by Tukey's post hoc test. ###p < 0.001 and ####p < 0.0001 compared to the control group; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, and ∗∗∗∗p < 0.0001 compared with the ethanol-fed group; ap < 0.05, aap < 0.01, and aaap < 0.001 compared with the E + probiotic V group; bp < 0.05, bbp < 0.01, and bbbp < 0.001 compared with the E + Met group.