Table 2.
SARS-CoV-2 IgG responses as determined by lateral flow immunochromatography following full-dose vaccination with Comirnaty® in SARS-CoV-2-naïve or recovered nursing home residents
| Gradinga/Timing of specimen collection after second vaccine dose | Study group |
|
|---|---|---|
| SARS-CoV-2-naïve n (%) | SARS-CoV-2-recovered n (%) | |
| 0 | ||
| 12−29 days | 3/52 (5.8%) | 0/2 (0%) |
| 30−59 days | 4/28 (14.3%) | 0/13 (0%) |
| 60−89 days | 14/104 (13.5%) | 4/177 (2.3%) |
| ≥90 days | 119/401 (29.7%) | 2/90 (2.2%) |
| 1+ | ||
| 12−29 days | 1/52 (1.9%) | 0/2 (0%) |
| 30−59 days | 11/28 (39.3%) | 1/13 (7.7%) |
| 60−89 days | 42/104 (40.4%) | 20/177 (11.3%) |
| ≥90 days | 147/401 (36.7%) | 4/90 (4.4%) |
| 2+ | ||
| 12−29 days | 13/52 (25%) | 1/2 (50%) |
| 30−59 days | 12/28 (42.9%) | 8/13 (61.5%) |
| 60–89 days | 35/104 (33.7%) | 92/177 (52%) |
| ≥90 days | 120/401 (29.9%) | 49/90 (54.4%) |
| 3+ | ||
| 12−29 days | 35/52 (67.3%) | 1/2 (50%) |
| 30−59 days | 1/28 (3.6%) | 4/13 (30.8%) |
| 60−89 days | 13/104 (12.5%) | 61/177 (34.5%) |
| ≥90 days | 15/401 (3.7%) | 35/90 (38.9%) |
a
IgG line intensity was scored visually using a 4-level scale: 0, negative result; 1+, weak positive result (intensity of test band lower than control band); 2+, positive result (intensity of test band equal to control line); 3+, strong positive result (intensity of test band greater than control line).