Table 1.

Patients characteristics following a negative trial

Patient	Age (years)	Sex (f=female/m=male)	Previous spine surgery	Trial phase (days)	Comorbidities	Main reason for treatment failure
1	77	f	Multiple surgeries with lumbar stabilization and decompression for DDD L1-L5	17	Depressive disorder under stable medication, alcohol abuse, arterial hypertension, prior hypertensive ICH	Lack of compliance
2	51	m	Discectomy and re-discectomy for disc herniation L4-S1	21	Arterial hypertensive disease, smoking	Insufficient pain reduction
3	89	m	Multiple surgeries with stabilization and decompression for DDD L4-L5	5	Periphery arterial disease, polyneuropathy, smoking, carotid stenosis, renal insufficiency	Lack of compliance
4	68	f	Decompression for spinal stenosis L3-S1	3		Insufficient pain reduction
5	40	f	Stabilization and discectomy for thoracic disc herniation Th11-Th12	4	Depressive disorder under stable medication, smoking
6	79	m	Multiple surgeries with stabilization L2-L4 and decompression for DDD and spondylolisthesis	15	Parkinson’s disease, arterial hypertensive disease, renal insufficiency	Lack of compliance and insufficient pain reduction