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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Prostaglandins Other Lipid Mediat. 2021 Jun 17;156:106577. doi: 10.1016/j.prostaglandins.2021.106577

Fig. 3. Antagonism of LPAR1 signaling down-regulates Cd36 mRNA expression in the MCD-fed mouse liver.

Fig. 3.

Mice fed the MCD diet for 10 days were treated with BrP-LPA (BrP: broad LPAR antagonist), AM095 (AM: LPAR1 antagonist), or control DMSO on day 5, 7, and 9 (male, n=3 for each group). mRNA expression of the liver tissues was analyzed by QPCR. mRNA expression values were normalized against Gapdh. Each value is the mean ± SD of triplicate measurements. *, p < 0.05; **, p<0.01.