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Factors affecting sex-differences in young and old adipose tissue
| Male | Female | |||
|---|---|---|---|---|
| Young | Old | Young | Old | |
| Testosterone | ⬆⬆ | ⬇ | ⬇ | ⬆ |
| Estrogen | ⬇ | ? | ⬆ | ? |
| Inflammatory cytokines | ⬆ | ⬆⬆ | ⬇ | ⬆ |
| Inflammatory monocytes | ⬆ | ⬆⬆ | ⬇ | ⬆ |
| Resident macrophages | ⬆ | ⬆ | ⬆⬆ | ⬆⬆ |
| Recruited macrophages | ⬆⬆ | ⬆⬆ | ⬆ | ⬆ |
| Dendritic cells | ⬆ | ⬇ | ⬇ | ? |
| CD8+ T cells | ⬆ | ⬆ | ⬆ | ⬆⬆ |
| Tregs | ⬆ | ⬆ | ? | ⬇⬇ |
| B cells | ⬆ | ⬆ | ⬆ | ⬆⬆ |
⬆⬆ Arrows indicate high and low
? Indicates inconclusive evidence
