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. 2021 Jun 11;38(9):2371–2381. doi: 10.1007/s10815-021-02255-5

Table 2.

Effect of human serum albumin on embryo development

Recombinant HSA Vitrolife HSA Sage HSA
48-h culture (day 3)
< 8cell (delayed) (%) 70.0 65.0 73.0
8 cell (%) 17.0a 19.0a 12.0b
Compacting (%) 8.0 12.0 12.0
72-h culture (day 4)
Morula (%) 31.4 35.0 32.3
Early blastocyst (%) 10.2a 13.2ab 18.2b
Blastocyst (%) 18.1a 17.5a 11.4b
Expanded and hatching blastocyst (%) 15.7 17.8 16.2

Embryo development data is expressed as percentage of presumptive zygote that reached each development stages. N = 361, 355, and 347 embryos for Recombinant, Vitrolife, and Sage HSA respectively (15 replicate experiments). Different superscript letters denote significance between treatment groups within a row (P < 0.05). HSA human serum albumin