Effects of blocking TRPV1 on aortic arch baroreceptor discharges. A Baroreceptor discharges recorded before (control group) and after perfusion with 20 µmol/L ruthenium red (RR), and after removal of RR with perfusate (wash group). B Statistical analysis of the effect of 20 μmol/L RR (n = 4; ***P <0.001 vs control group). C Baroreceptor discharges recorded before (control group) and after perfusion with different concentrations of capsazepine, and after removal of capsazepine with perfusate (wash group). D Statistical analysis of the effect of capsazepine (n = 3; ***P <0.001 vs control group, ##P <0.01 for 30 μmol/L vs 50 μmol/L capsazepine, ###P <0.001 for wash vs 50 μmol/L capsazepine; binwidth, 0.05 s). E Expansion diagram of the boxed area in (C). ANA, aortic nerve activity. IAP, intravascular aortic pressure. 1 mmHg = 0.133 kPa.