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. 2021 Sep 21;8:710079. doi: 10.3389/fmed.2021.710079

Table 2.

Vitreous levels of erythropoietin and vascular endothelial growth factor (VEGF).

Variables MH and ERM PDR P- value P1 P2 P3
(control group) Non-IVR IVR # § &
EPO (mIU/ml)
Mean ± SD 18.96 ± 13.30 99.29 ± 27.77 68.57 ± 41.47 <0.001 <0.001 0.001 0.04
95% CI 10.02–27.90 83.25–115.3 38.91–98.24
VEGF (pg/ml)
Mean ± SD 10.98 ± 0.98 836.30 ± 899.5 13.22 ± 2.72 0.001 0.003 0.99 0.004
95% CI 10.32–11.64 316.90–1356 11.27–15.17

MH, macular hole; ERM, epiretinal membrane; DM, diabetes mellitus; PDR, proliferative diabetic retinopathy; #Control vs. Non-IVR; §Control vs. IVR; &Non-IVR vs. IVR.

Bold value indicates p < 0.05, which are statistically significant.