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. 2021 Sep 21;12:726428. doi: 10.3389/fimmu.2021.726428

Table 1.

Baseline characteristics of study participants.

Total (n = 30) Relapsing (n = 17) Non-relapsing (n = 13) P-value
Demographics
Age (yrs) 11.6 ± 6.9 11.1 ± 6.7 12.3 ± 7.4 0.65
Sex n (%) 0.24
Female 6 (20) 2 (12) 4 (31)
Male 24 (80) 15 (88) 9 (69)
Treatment 0.29
Rituximab n (%) 15 (50) 10 (59) 5 (38)
Ofatumumab n (%) 15 (50) 7 (41) 8 (62)
Prior rituximab use, n (%) 12 (40) 6 (35) 6 (46) 0.36
Number of prior relapses, n 1.5 (1-10) 2 (1-10) 1 (1-6) 0.52
Immunosuppressive drugs at enrollment (T0), n (%)
Steroids 30 (100) 17 (100) 13 (100) 1.0
Tac 16 (53) 9 (53) 7 (58) 0.96
CsA 13 (43) 8 (47) 5 (38) 0.63
Labs
Serum Creatinine (mg/dL) 0.54 ± 0.24 0.53 ± 0.27 0.55 ± 0.20 0.85
Serum Albumin (g/dL) 3.73 ± 0.64 3.74 ± 0.55 3.71 ± 0.77 0.88
Cholesterol (mg/dL) 210 ± 61 192 ± 57 232 ± 61 0.09
eGFR (ml/min) 137 ± 38 142 ± 39 129 ± 37 0.35
IgA (mg/dL) 658 ± 231 638 ± 243 685 ± 221 0.59
IgM (g/dL) 166 ± 109 162 ± 127 171 ± 84 0.82
IgG (mg/dL) 144 ± 83 150 ± 99 134 ± 60 0.60
Proteinuria (mg/24 h) 99 ± 83 116 ± 104 78 ± 36 0.18

Data are mean ± SD number (%), or median (range). p-value compares the two treatment groups in a two-tailed t-test of heteroscedastic variance or chi squared. Tac, tacrolimus; CsA, cyclosporine.