Table 4.
Some recent studies on extraction, isolation, and quantifications of curcumin.
| Sample types | Extraction methods | Extraction conditions | Extraction yield (%) | Identification and quantification methods | Column type | Conditions for identification and quantification | Concentration of compound (mg/g dry weight) | References | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Solvent type | Time (min) | Temperature (°C) | Column/plate dimension (mm × mm) | Particle size (μm) | Injected volume (μL) | |||||||
| Powder | Surfactant-free microemulsion (SFME) extraction | Triacetin: Ethanol: water (36:24:40) | - | - | 0.921% | HPLC | C18 | 150 × 2.1 | 0.03 | 10 | 9.21 ± 0.32 | (140) |
| Powder | Refluxing | Dichloromethane | 60 | - | 81.81–86.36 | Thin Layer Chromatography (TLC) | - | 100 × 200 | - | - | 818.1–863.6 | (138) |
| Powder | Ionic liquid bath | 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl) imide | 10–60 | 25–55 | 0.76–2.94 | HPLC (Agilent 1100) | C18 | 150 × 4.6 | 5 | 20 | 29.4 | (139) |
| Powder | Dissolving | Ethanol (95%) | 10,080 | Room temperature | 15 | Column Chromatography | - | - | - | - | 150 | (144) |
| Powder | Soxhlet method | Ethanol | 480 | 70 | 12.67 | Column Chromatography | - | - | - | - | 788 | (129) |
| Powder | Soxhlet method | Petroleum ether | 60 | - | 1.55–5.163% | UHPLC | C 18 | 100 × 2.1 | 1.7 | 10 | 6.58 ± 0.023–21.31 ± 0.301 | (66) |
| Powder | Enzyme-assisted ionic liquid extraction | N,N-dipropyl ammonium and N, N-dipropylcarbamate | 120 | Room temperature | 1.48–3.95 | HPLC (Smartline, Knauer, Germany) | C 18 | 250 × 4.6 | 0.45 | - | 57.3 | (128) |
| Powder | Subcritical water extraction | Water | 60 | 140 | 76 | HPLC | C 18 | 250 × 4.6 | 0.45 | - | 38 | (137) |
| Powder | Subcritical solvent extraction | Water | 120 | 60 | 10.49–13.96 | HPLC Agilent system (1200 series, Agilent Technologies, Santa Clara, CA, USA) | C 18 | 150 × 4.6 | 5 | 20 | 49.4 | (143) |