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. 2021 Sep 21;11:748229. doi: 10.3389/fonc.2021.748229

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Copyright © 2021 Gómez Vecchio, Neimantaite, Corell, Bartek, Jensdottir, Reinertsen, Solheim and Jakola

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Circular bar plots—proximity to predefined eloquent regions by molecular subgroups according to WHO 2016. (A) IDH wild-type astrocytomas N=82, (B) IDH-mutated astrocytomas N=67, and (C) Oligodendrogliomas N=73. PreC, Precentral; PostC, Postcentral; PeriCal, Pericalcarine; Hipp, Hippocampus; ParaHipp, Para hippocampus; SupMarg, Supramarginal; ParsTri, Pars Triangularis; ParsOp, Pars Opercularis; InfPar, Inferior parietal; CS, Corticospinal; OR, Optic radiations; IFOF, Inferior fronto-occipital fasciculus; SLF, Perisylvian anterior, posterior, and long components of the superior longitudinal fasciculus; AF, Arcuate fasciculus. “L” and “R” indicate left and right sides. Size and color intensity represent the percentage of tumors in the proximity to predefined eloquent regions by tumor groups. Fisher–Freeman–Halton exact tests were used when appropriate for three-group comparison between IDH wild-type astrocytoma, IDH-mutated astrocytoma, and oligodendroglioma. *P value equal or inferior to 0.002.