TABLE 5.

Multiple logistic regression for factors correlated with the incidence of severe exacerbation during 6 months follow-up.

Characteristics (N = 695)	aOR	a95%IC	p-value
Inhalation therapy
ICS/LABA/LAMA	Reference
LAMA	0.53	0.23–1.23	0.138
LAMA/LABA	1.95	1.04–3.66	0.038
ICS/LABA	0.63	0.21–1.89	0.408
Others	0.76	0.25–0.31	0.631

Note: Factors in the logistic model: sex, age, treatment status at baseline, exacerbation in the past 1 year, severe exacerbation in the past 1 year, CAT score, mMRC score, Gold stage, group B/D, inhalation therapy; the bold p-values indicate statistical significance.

Abbreviations: CAT, COPD assessment test; mMRC, modified medical research council dyspnea scale; LABA, long-acting β2-agonist; LAMA, long-acting muscarinic antagonist; ICS, inhaled corticosteroid; aOR, adjusted odds ratio; a95% CI, adjusted 95% confidence interval.