FIGURE 2.

CXXC5 over-expression suppresses HSC activation. (A–C) LX-2 cells were infected with adenovirus carrying CXXC5 expression vector (Ad-CXXC5) or GFP (Ad-GFP). Gene expression levels were examined by qPCR and Western. Cell proliferation was measured by EdU staining. (D–F) Primary murine hepatic stellate cells were infected with adenovirus carrying CXXC5 expression vector (Ad-CXXC5) or GFP (Ad-GFP). Cell proliferation was measured by EdU staining. All experiments were repeated three times and one representative experiment is shown. *p < 0.05.