Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 21;12:688493. doi: 10.3389/fimmu.2021.688493

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Rivas, Durmaz, Kloetgen, Chin, Chen, Bhinder, Koren, Viny, Scharer, Boss, Elemento, Mason and Melnick

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Decreased cohesin levels predict poor survival in DLBCL patients. (A) Kaplan-Meier overall survival curves for DLBCL patients (n=322) in BCCA cohort clustered with the Smc3 haploinsufficient gene signature (6). (B) Kaplan-Meier progression-free survival curves for DLBCL patients (n=322) in BCCA cohort clustered with the Smc3 haploinsufficient gene signature (6). (C) Kaplan-Meier overall survival curves for GCB-subtype DLBCL patients (n=186) in cluster 1 and 2. (D) Kaplan-Meier progression-free survival curves for GCB-subtype DLBCL patients (n=186) in cluster 1 and 2. (E) Univariate Cox regression analysis, and (F) multivariate Cox regression analysis were performed in two cohorts of DLBCL patients (cohort 1, n = 322 individuals; cohort 2, n = 757 individuals). In both cases, SMC1A, RAD21, STAG2 and STAG1 expression levels were used as a continuous variable. Multivariate analysis was adjusted by age, sex and DLBCL subtype of the individual. Error bars represent 95% confidence intervals of the hazard ratio.