TABLE 5.

Gene ontology (GO) analysis of five typical pathways associated with ovarian cancer (OC).

Term/gene function	Genes
GO:0006468 ∼protein phosphorylation	NUAK2, FASTK, PASK, PKMYT1, RPS6KB2, AURKA, AURKB, PRKY, CCNE1, ACVR1B, ADCK2, CSNK2A1, PAK2, TLK1, CDK16, CSK, LIMK1, PHKG2, PRKCI, PKN1, MINK1, PBK, SRPK1, GAK, CCND1, MAST2, HIPK2, BUB1B, WNT11, EIF2AK2, LRRK1, KALRN, NEK2, MAP4K1, MAPKAPK2, BUB1, CAMK2B, DYRK2, STK19, RUNX3, AATK, CSNK1A1, TAF1, TRIO, BIRC5, ILF3, IKBKE, CSNK1E, GSK3A, GRK6, TSSK2, JAK3, CIT, IKBKB
GO:0098609 ∼cell–cell adhesion	ALDOA, YWHAZ, SEPT2, ZC3HAV1, RANGAP1, SFN, TAGLN2, PKM, EPCAM, PAK6, BZW2, PAK2, DDX3X, CC2D1A, CLINT1, TES, GOLGA2, HIST1H3J, STX5, MYO6, BAIAP2, TRIM29, CBL, DOCK9, PFKP, LYPLA2, MICALL1, CORO1B, EPB41L1, CCNB2, HIST1H3B, HIST1H3E, ERC1, HIST1H3F, DBN1, HIST1H3G, HIST1H3H, PUF60, HIST1H3I, SEPT9
GO:0046777 ∼protein autophosphorylation	FGFR2, TAF1, FLT1, NEK2, PASK, MAP4K1, TTK, MINK1, AURKA, CAD, MAPKAPK2, AURKB, EPHB3, PRKX, ACVR1B, DDR1, PTK2, PAK2, MAP3K10, TSSK2, CAMK2B, EIF2AK2, CSK, MELK
GO:2001238 ∼positive regulation of extrinsic apoptotic signaling pathway	BID, LTBR, PAK2, TNFRSF12A, PML, RBCK1, WWOX
GO:0043066 ∼negative regulation of apoptotic process	STIL, CLDN7, PPARD, YWHAZ, HTATIP2, MCL1, NUAK2, AURKA, BCL2L1, SOX9, ADORA1, EPCAM, PTK2, PAK2, DDX3X, ITCH, ARHGDIA, DHCR24, KIF14, CDK1, PRAME, SOCS3, SMAD6, CBL, TP53, PRKCI, BIRC5, HMGA2, PPIF, ATF5, PA2G4, HSP90B1, MSX1, MAD2L1, UCP2, VEGFA, TFAP2A, WNT11, IKBKB, EIF2AK2, CLEC5A, GSTP1, BARD1
p ≤ 0.01