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. 2021 Sep 21;12:707977. doi: 10.3389/fimmu.2021.707977

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Copyright © 2021 Jiang, Zhang, Liu, Ding, Liu, Tian, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sequence characteristics of the mAbs. (A) Multiple alignment of the variable regions of 15G9, 12C10 and 10D2. The black boxes indicated the complementarity-determining regions (CDRs). (B) Structural alignment of VHs for 15G9, 12C10 and 10D2. (C) Structural alignment of VLs for 15G9, 12C10 and 10D2. 15G9 (darksalmon), 12C10 (palecyan), 10D2 (slate). The CDRs of 15G9, 12C10, 10D2 were marked as red, cyan and blue, respectively. The variable region sequences of these mAbs had been submitted to GenBank and the accession numbers were MZ751046, MZ751047, MZ751048, MZ751049 and MZ751050, respectively.