Table 3.
Sequence characteristics of the SARS-CoV-2 mAbs.
| Mab Name | CDRs | Closest germline gene and allele | |||||
|---|---|---|---|---|---|---|---|
| CDR1 | CDR2 | CDR3 | V | D | J | ||
| VH | 15G9 | GYTFTDYA | ISSHNGNR | AIFDYDFDY | IGHV1-67*01 | IGHD2-4*01 | IGHJ2*01 |
| 10D2 | GYTFTKYR | INTNTGES | ASSMDY | IGHV9-3*02 | IGHD3-3*01 | IGHJ4*01 | |
| 12C10 | GFTFSNYS | ISNGGGYI | GRPRPEKEFISTSTAMDH | IGHV5-9-3*01 | IGHD1-2*01 | IGHJ4*01 | |
| VL | 15G9 | KSVSTSGYSY | LVS | QHIRELTRS | IGKV3-12*01 | – | IGKJ2*01 |
| 10D2 | KSVSTSGYSY | LVS | QHIRELTRS | IGKV3-12*01 | – | IGKJ2*01 | |
| 12C10 | QSLLYSSYQKNY | WAS | QQYYSYPFT | IGKV8-30*01 | – | IGKJ4*01 | |
The number *01 signifies that any new polymorphic sequence will be described by comparison to that allele *01.