Table 1.
Statistical analysis of clinical characteristics of IDC/DCIS patients in the GSE26304 data set.
| Samples | p-value | ||||
|---|---|---|---|---|---|
| Total (N=67) | DCIS (N=31) | IDC (N=36) | |||
| tp53mut | |||||
| tp53_WT | 58 (86.6%) | 26 (83.9%) | 32 (88.9%) | 0.809 | |
| tp53_Mut | 9 (13.4%) | 5 (16.1%) | 4 (11.1%) | ||
| Age (years) | |||||
| <=55 | 28 (41.8%) | 14 (45.2%) | 14 (38.9%) | 0.787 | |
| >55 | 39 (58.2%) | 17 (54.8%) | 22 (61.1%) | ||
| Grade | |||||
| 1 | 3 (4.5%) | 2 (6.5%) | 1 (2.8%) | 0.00209 | |
| 2 | 41 (61.2%) | 12 (38.7%) | 29 (80.6%) | ||
| 3 | 23 (34.3%) | 17 (54.8%) | 6 (16.7%) | ||
| Tumor Size | |||||
| Large | 27 (40.3%) | 26 (83.9%) | 1 (2.8%) | <0.001 | |
| Small | 40 (59.7%) | 5 (16.1%) | 35 (97.2%) | ||
| X-ray | |||||
| 1 | 39 (58.2%) | 13 (41.9%) | 26 (72.2%) | 0.024 | |
| 2 | 28 (41.8%) | 18 (58.1%) | 10 (27.8%) | ||
| Chemotherapy | |||||
| 1 | 2 (3.0%) | 0 (0%) | 2 (5.6%) | 0.54 | |
| 2 | 65 (97.0%) | 31 (100%) | 34 (94.4%) | ||
| Hormone treatment | |||||
| 1 | 10 (14.9%) | 0 (0%) | 10 (27.8%) | 0.00454 | |
| 2 | 57 (85.1%) | 31 (100%) | 26 (72.2%) | ||
| Pam50 Class | |||||
| BASAL | 12 (17.9%) | 6 (19.4%) | 6 (16.7%) | 0.648 | |
| HER 2 | 7 (10.4%) | 2 (6.5%) | 5 (13.9%) | ||
| LUMINALA | 15 (22.4%) | 7 (22.6%) | 8 (22.2%) | ||
| LUMINAL B | 18 (26.9%) | 7 (22.6%) | 11 (30.6%) | ||
| NORMAL | 15 (22.4%) | 9 (29.0%) | 6 (16.7%) | ||
Significance: 1 represents No, 2 represents Yes.