Table 3.
Association of mean FC in the DMN and amyloid burden
|
FC DMN
Regression coefficient (β) |
P-value | |
|---|---|---|
| CSF Aβ 42/40 ratio | 0.17 | 0.020 |
| BPND in the PCC | −0.15 | 0.006 |
| BPND in precuneus | −0.09 | 0.165 |
| BPND in MOF cortex | −0.09 | 0.153 |
All values were transformed to z-scores. All GEE analyses took into account family ID as a random factor and were corrected for age, sex, and normalized GM volume.
Aß, amyloid ß; BPND, non-displaceable binding potential; DVR, distribution volume ratio; MOF, medio-orbitofrontal cortex; PCC, posterior cingulate cortex; GEE, generalized estimating equations.