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The number of particle therapy centers in operation and publications on “angle optimization” in the past 10 years (2010–2020). The number of facilities was verified on the webpage of the Particle Therapy Cooperative Group (PTCOG https://www.ptcog.ch/). The papers were filtered by searching for the following keywords: “carbon ion radiotherapy” OR “proton radiotherapy” OR “angle optimization” using Google Scholar (https://scholar.google.com/).
