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. 2021 Sep 21;12:741801. doi: 10.3389/fphar.2021.741801

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Copyright © 2021 Yu, Lin, Yang, Wei, Chen, Liu, Zhong, Chen, Pei and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptomic assay and bioinformatics analysis. (A) Compared Sham group with UUO group, filtering of DEGs was presented by volcano. (B) Compared UUO hirudin-treated group with UUO group, filtering of DEGs was presented by volcano. (C) Venn diagram of overlapping genes derived from transcriptome analysis in a pairwise comparison. Red color represents upregulated genes, while green color shows downregulated genes.