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. 2021 Sep 21;12:741801. doi: 10.3389/fphar.2021.741801

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Copyright © 2021 Yu, Lin, Yang, Wei, Chen, Liu, Zhong, Chen, Pei and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional analysis of the kidney transcriptome by hirudin treatment. (A) Gene Set Enrichment Analysis (GSEA) of hirudin treatment-related key pathways. (B) biological processes (BP) of GO analysis of hirudin treatment-related functional annotations. (C) molecular function (MF) of GO analysis of hirudin treatment-related functional annotations. (D) cellular component (CC) of GO analysis of hirudin treatment-related functional annotations. (E) Schematic diagram of hirudin against RIF through PI3K/Akt pathway.