. 2021 Jul 14;17(4):524–533. doi: 10.3988/jcn.2021.17.4.524

Table 2. Results of univariate and multivariate regression analyses of carpal tunnel syndrome.

		Univariate			Multivariate (full model)			Multivariate (reduced model)
		HR	95% CI	p	HR	95% CI	p	HR	95% CI	p
Age at the start of the study (in 2003), years
	40–49	Ref.			Ref.			Ref.
	50–59	1.047	0.994–1.103	0.0846	-	-		-	-
	60–69	0.722	0.675–0.771	<0.0001^*	0.590	0.551–0.632	<0.0001^*	0.590	0.551–0.631	<0.0001^*
	≥70	0.348	0.302–0.402	<0.0001^*	0.312	0.270–0.360	<0.0001^*	0.312	0.270–0.360	<0.0001^*
Sex
	Male	Ref.			Ref.			Ref.
	Female	4.313	4.083–4.555	<0.0001^*	4.431	4.192–4.685	<0.0001^*	4.429	4.190–4.682	<0.0001^*
Body mass index at the start of the study (in 2003), kg/m²
	<18.5	Ref.			Ref.			Ref.
	18.5–22.9^*	1.994	1.544–2.447	<0.0001^*	1.604	1.274–2.019	<0.0001^*	1.604	1.274–2.020	<0.0001^*
	23.0–24.9^*	2.367	1.880–2.981	<0.0001^*	2.088	1.658–2.629	<0.0001^*	2.089	1.658–2.630	<0.0001^*
	25.0–29.9^*	2.725	2.167–3.428	<0.0001^*	2.450	1.947–3.083	<0.0001^*	2.451	1.948–3.084	<0.0001^*
	30.0–35.0^*	3.710	2.884–4.771	<0.0001^*	2.726	2.119–3.508	<0.0001^*	2.728	2.120–3.510	<0.0001^*
Comorbidities
	Diabetes mellitus	1.041	0.972–1.114	0.2510
	Rheumatoid arthritis	1.932	1.783–2.095	<0.0001^*	1.540	1.418–1.673	<0.0001^*	1.543	1.421–1.674	<0.0001^*
	Gout	0.888	0.719–1.095	0.2665	-	-		-	-
	End-stage renal disease	0.715	0.423–1.207	0.2090	-	-		-	-
	Hypothyroidism	1.611^*	1.346–1.928	<0.0001^*	1.049	0.876–1.256	0.6064	-	-
	Raynaud's syndrome	2.718^*	1.543–4.787	0.0005^*	2.267^*	1.286–3.996	0.0047	2.273^*	1.289–4.007	0.0045^*

*p<0.05.

CI: confidence interval, HR: hazard ratio, Ref.: reference.