Table 3.
Univariate and multivariate Cox regression analyses of factors predictive of overall survival in type 2 PRCC patients.
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p | HR | 95% CI | p | |
| Gender (male vs. female) | 1.014 | 0.364–2.821 | 0.979 | – | – | – |
| Age (>55 vs. ≤55) | 1.077 | 0.430–2.695 | 0.875 | – | – | – |
| Tumor location (left vs. right) | 1.255 | 0.510–3.092 | 0.621 | – | – | – |
| Tumor size (>5.8 cm vs. ≤5.8 cm) | 5.224 | 1.732–15.753 | 0.003 | 1.706 | 0.534–5.451 | 0.368 |
| Surgical procedures (RN vs. PN) | 9.531 | 1.272–71.431 | 0.028 | 3.346 | 0.403–27.754 | 0.263 |
| T stage (III/IV vs. I/II) | 8.425 | 3.305–21.479 | <0.001 | 4.489 | 1.506–13.382 | 0.007 |
| WHO/ISUP grade (G3/4 vs. G1/2) | 18.848 | 2.508–141.618 | 0.004 | 9.701 | 1.235–76.171 | 0.031 |
| Microvascular invasion (yes vs. no) | 4.225 | 1.602–11.142 | 0.004 | 1.671 | 0.542–5.148 | 0.371 |
| Tumor necrosis (yes vs. no) | 1.072 | 0.407–2.823 | 0.888 | – | – | – |
| Sarcomatoid differentiation (yes vs. no) | 4.410 | 0.575–33.809 | 0.153 | – | – | – |
PRCC, papillary renal cell carcinoma; RN, radical nephrectomy; PN, partial nephrectomy; WHO/ISUP, WHO International Society of Urological Pathology.