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. 2021 Sep 21;12:736972. doi: 10.3389/fendo.2021.736972

Table 1.

Associations between metabolic syndrome and thyroid nodules in TIDE survey.

Parameters, % (n) Overall Non-Thyroid Nodule Thyroid Nodules p OR 95%CI p value
(N = 56729) (N = 46099) (N = 10630)
MetS 28.7 (16308) 26.6 (12251) 38.2 (4057) 0.000 1.069 1.011-1.129 0.018
 Male 32.9 (9733) 31.2 (7769) 42.3 (1964) 0.000 1.132 1.047-1.224 0.002
 Female 24.2 (6575) 21.2 (4482) 35.0 (2093) 0.000 0.999 0.923-1.081 0.985
Central obesity 34.4 (19526) 32.2 (14864) 43.9 (4662) 0.000 1.108 1.044-1.175 0.001
 Male 39.0 (11518) 37.3 (9303) 47.7 (2215) 0.000 1.120 1.027-1.220 0.010
 Female 29.5 (8008) 26.3 (5561) 40.9 (2447) 0.000 1.081 0.996-1.174 0.063
Hypertriglyceridemia 28.2 (15977) 27.6 (12741) 30.4 (3236) 0.000 0.969 0.920-1.020 0.229
 Male 34.8 (10285) 34.5 (8600) 36.3 (1685) 0.018 0.980 0.912-1.053 0.575
 Female 21.0 (5692) 19.6 (4141) 25.9 (1551) 0.000 0.950 0.882-1.023 0.175
Low HDL-C 20.3 (11492) 20.1 (9255) 21.0 (2237) 0.025 0.899 0.849-0.951 0.000
 Male 14.7 (4333) 14.7 (3657) 14.6 (676) 0.848 0.954 0.868-1.048 0.326
 Female 26.4 (7159) 26.4 (5598) 26.1 (1561) 0.564 0.869 0.810-0.933 0.000
Abnormal BP 43.8 (24835) 41.3 (19051) 54.4 (5784) 0.000 1.129 1.073-1.188 0.000
 Male 52.2 (15444) 50.4 (12564) 62.0 (2880) 0.000 1.080 1.004-1.161 0.038
 Female 34.6 (9391) 30.6 (6487) 48.5 (2904) 0.000 1.170 1.090-1.256 0.000
Hyperglycemia 45.8 (26008) 43.3 (19978) 56.7 (6030) 0.000 1.070 1.019-1.123 0.007
 Male 48.5 (14348) 46.5 (11593) 59.3 (2755) 0.000 1.079 1.005-1.159 0.036
 Female 42.9 (11660) 39.6 (8385) 54.7 (3275) 0.000 1.063 0.994-1.137 0.075

TIDE, Thyroid disorders, Iodine status and Diabetes Epidemiological; MetS, metabolic syndrome; HDL-C, high density lipoprotein cholesterol; BP, blood pressure.