Date	Events
2009	Posterior mitral valve leaflet prolapse and mild to moderate mitral regurgitation first detected on transthoracic echocardiography (TTE)
2011	Posterior ST-elevation myocardial infarction treated with aspiration thrombectomy
November 2019	Last dental procedure (filling) before symptom onset
January 2020	Low grade fever up to 37.5°C and symptomatic treatment
February 2020	Antibiotic treatment with cefuroxime 500 mg b.i.d. started due to persistent low-grade fever, cough, and malaise
March 2020	Second antibiotic treatment
April 2020	Third antibiotic treatment
May 2020	Fever up to 38.5°C with negative RT-PCR and Rapid IgM/IgG tests for COVID-19 and fourth course of antibiotic therapy with clarithromycin sedimentation rate 500 mg/day
2 June 2020	Visit to cardiologist and admission to hospital after a mobile structure is detected on TTE
June–July 2020	Intravenous antibiotic therapy with vancomycin and ceftriaxone
10 July 2020	Transient ischaemic attack
16 July 2020	Mitral valve replacement