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. 2021 Oct 4;4(10):e2127378. doi: 10.1001/jamanetworkopen.2021.27378

Table 1. Maternal and Neonatal Characteristics by Mode of Delivery Among Kidney and Liver Transplant Recipientsa.

Characteristic Kidney transplant Liver transplant
SCD TOL-CD TOL-VD SCD TOL-CD TOL-VD
Maternal
Mothers, No. 459 282 694 105 73 252
Age, mean (SD), y 31.0 (6.6)b 29.4 (5.1) 30.1 (5.0) 29.9 (5.4) 29.4 (5.8) 28.8 (5.2)
BMI, median (IQR) 23.8 (21.0-28.6)b 25.1 (21.6-30.7) 23.0 (20.4-26.6) 23.8 (21.6-29.2)b 24.3 (22.0-28.4) 22.5 (20.3-26.4)
Nulliparous 224 (48.8)b 195 (69.1) 401 (57.8) 37 (33.3)b 55 (75.3) 122 (19.0)
Multiple gestations 33 (7.2)b 4 (1.4) 16 (2.3) 10 (9.5)b 0 4 (1.6)
In vitro fertilization 19 (4.1)c 5 (1.8) 11 (1.6) 9 (8.6)c 1 (1.4) 4 (1.6)
Year of delivery
1968-1999 217 (47.3) 152 (53.9) 370 (53.3) 23 (21.9) 20 (27.4) 77 (30.1)
2000-2019 242 (52.7) 130 (46.1) 324 (46.7) 82 (78.1) 53 (72.6) 175 (69.4)
Race and ethnicity
Asian or Asian Pacific Islander 24 (5.2) 17 (6.0) 48 (6.9) 5 (4.8) 4 (5.5) 9 (3.6)
Black 28 (6.1) 20 (7.1) 41 (5.9) 6 (5.7) 11 (15.1) 16 (6.3)
White 324 (70.6) 198 (70.2) 499 (71.9) 72 (68.6) 46 (63.0) 184 (73.0)
Otherd 48 (10.5) 20 (7.1) 54 (7.8) 17 (16.2) 6 (8.2) 33 (13.1)
Unknown 35 (7.6) 27 (9.6) 52 (7.5) 5 (4.8) 6 (8.2) 10 (4.0)
Prenatal care 380 (82.8) 234 (83.0) 578 (83.2) 90 (85.7) 54 (74.0) 200 (79.4)
Transplant center delivery 137 (29.8) 107 (37.9) 240 (34.6) 28 (26.7) 25 (34.2) 77 (30.6)
Transplant-to-conception interval, median (IQR), y 4.9 (2.5-8.2)c 3.9 (2.1-6.6) 4.4 (2.3-7.6) 7.4 (3.6-15.3) 6.4 (2.1-12.5) 6.2 (3.0-11.7)
Chronic hypertension 121 (26.4) 72 (25.5) 198 (28.5) 17 (16.2) 10 (13.7) 26 (10.3)
Hypertensive disorder during pregnancy 198 (43.1)b 137 (48.6) 224 (32.3) 30 (28.6) 24 (32.9) 62 (24.6)
Diabetes
Gestational 26 (5.7) 11 (3.9) 22 (3.2) 9 (8.6) 3 (4.1) 11 (4.4)
Pregestational 26 (5.7)b 23 (8.2) 13 (1.9) 4 (3.8) 4 (5.5) 5 (2.0)
Placental abruption 8 (1.7)c 7 (2.5) 3 (0.4) 3 (2.9) 2 (2.7) 5 (2.0)
Neonatal
Neonates, No. 494 285 707 113 73 254
Sex
Female 219 (44.3) 135 (47.4) 351 (49.6) 57 (50.4) 35 (47.9) 127 (50.0)
Male 275 (55.7) 150 (52.6) 356 (50.4) 56 (49.6) 38 (52.1) 125 (49.2)
Gestational age, median (IQR), wk 36 (33.0-37.9)b 37 (35.0-38.3) 37 (35.0-38.1) 37 (34.5-38.0)b 38 (35.0-39.0) 38 (36.0-39.4)
Birth weight, median (IQR), g 2495 (1860-2977)b 2750 (2084-3118) 2778 (2325-3141) 2736 (1973-3133)b 2892 (2353-3260) 2977 (2551-3345)
Weight percentile, median (IQR)e 35.2 (12.8-62.3) 30.2 (16.1-64.1) 32.8 (16.1-64.1) 38.4 (16.1-60.9) 30.2 (10.9-62.2) 39.3 (16.9-64.1)
Congenital anomalies 20 (4.1) 14 (4.9) 28 (4.0) 20 (4.1) 14 (4.9) 28 (4.0)

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CD, cesarean delivery; SCD, scheduled CD; TOL, trial of labor; VD, vaginal delivery.

a

Data are presented as number (percentage) of mothers or neonates unless otherwise indicated. Variables with more than 5% of data missing included BMI (kidney, 424 [29.5%]; liver, 77 [17.9%]), prenatal care (kidney, 117 [8.2%]; liver, 39 [9.1%]), and delivery at a transplant center (kidney, 359 [25.0%]; liver, 34 [7.9%]).

b

P ≤ .01.

c

P ≤ .05.

d

Other was an option provided by the Transplant Pregnancy Registry International investigators for self-reported race and ethnicity.

e

Fenton percentile for preterm neonates and World Health Organization percentile for term neonates.