Table 8. IC50 Values in the Enzymatic Assay for JAK2 Inhibition.
| compounds | IC50 (nM) |
|---|---|
| 1 | >10 000 |
| 3 | >10 000 |
| 4 | 807 (643–1007) |
| 5 | >10 000 |
| 6 | >10 000 |
| 7 | 637 (367–1076) |
| 8 | >10 000 |
| Tofacitinib | 31.4 (16–61) |
a
95% confidence limits are shown in brackets.
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