Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mitochondria reprogramming in tumor. Some oncoproteins or tumor suppressors function within mitochondria (such as IDH1/2, SDH, and FHs) generating oncogenic metabolites initiating tumor formation, and many others directly or indirectly affect mitochondrial function (mutations including but not limited to that in Pi3k/Akt /mTOR pathway, Tp53, and Myc) and reprograming mitochondria metabolism enabling tumor transformation
