Figure 4. WldS mice are protected from post-TBI-induced elevated ac-tau, AIS degradation, and tau mislocalization.
(A) WldS mice are resistant to post-TBI elevations in ac-tau in the brain (for each group n =4, *p < 0.05, **p < 0.01 versus WT+TBI group, one-way ANOVA; and Tukey’s post hoc analysis).
(B) WldS mice are resistant to post-TBI AIS degradation (scale bar, 5 μm).
(C) WldS mice are resistant to post-TBI tau mislocalization (scale bar, 5 μm).
In (B)-(C), each group n = 3, ****p < 0.0001 versus WT+TBI group, one-way ANOVA; and Tukey’s post hoc analysis. See also Figure S5.
