FIGURE 6.

DNase I suppressed metastasis under S. aureus infection in vivo. A, Representative images of lung tissues with 4T1 metastasis. Mice were treated with or without DNase I after S. aureus stimulation, and then 4T1 cells were injected. B, The results of lung weight and metastasis nudes in each groups were monitored. C, Representative H&E staining images of lung left lobe. Blank arrows represented metastasis nudes. Statistical analysis was performed by Student's paired t‐test between two groups, and one‐way ANOVA for three or more groups. Scale bars, 50 µm. Data represent three independent experiments and shown as mean ± SEM. ^**** P < .0001