FIGURE 5.
Antitumor activity of 5T4 CAR‐T cells in peritoneal tumor model. (A) 2 × 105 SKOV3‐luc cells were intraperitoneally injected into B‐NDG mice on day 0, and 2 × 106 5T4 CAR‐T cells were intraperitoneally injected 2 days later for treatment. The treatments were given every 2 days for a total of three times. We observed the growth of peritoneal tumors by bioluminescence imaging weekly. (B) Body weight curve of mice. (C) The overall survival of mice treated with the 5T4 CAR‐T cells, NT T cells or saline