Table 20.
Estimated Number of Casesa,b in the US of Brain and Other Central Nervous System Tumors Overall and by Behavior and Histology c, 2021, 2022
| Histology | 2021 | 2022 | ||||
|---|---|---|---|---|---|---|
| Malignant | Non-Malignant | Total | Malignant | Non-Malignant | Total | |
| Diffuse Astrocytic and Oligodendroglial Tumors | 17,080 | -- | 17,080 | 17,270 | -- | 17,280 |
| Diffuse astrocytoma | 1,490 | -- | 1,490 | 1,480 | -- | 1,480 |
| Anaplastic astrocytoma | 1,350 | -- | 1,350 | 1,320 | -- | 1,320 |
| Glioblastoma | 13,160 | 13,160 | 13,430 | 13,430 | ||
| Oligodendroglioma | 690 | 690 | 680 | 680 | ||
| Anaplastic oligodendroglioma | -- | -- | -- | -- | -- | -- |
| Oligoastrocytic tumors | -- | -- | -- | -- | -- | -- |
| Other Astrocytic Tumors | 1,170 | 460 | 1,630 | 1,170 | 800 | 1,970 |
| Pilocytic astrocytoma | 1,050 | 380 | 1,430 | 1,040 | 720 | 1,770 |
| Unique astrocytoma variants | 120 | 80 | 200 | 130 | 70 | 200 |
| Ependymal Tumors | 790 | 630 | 1,420 | 780 | 640 | 1,420 |
| Other Gliomas | 1,850 | -- | 1,850 | -- | -- | 1,900 |
| Glioma malignant, NOS | -- | -- | -- | -- | -- | |
| Other neuroepithelial tumors | -- | -- | -- | -- | -- | -- |
| Neuronal and Mixed Neuronal-Glial Tumors | 210 | 890 | 1,100 | 220 | 910 | 1,120 |
| Neuronal and mixed neuronal-glial tumors | 210 | 890 | 1,100 | 220 | 910 | 1,120 |
| Choroid Plexus Tumors | -- | -- | 170 | -- | -- | 170 |
| Tumors of the Pineal Region | 100 | 70 | 160 | 100 | 70 | 170 |
| Embryonal Tumors | 600 | -- | 600 | 590 | -- | 590 |
| Tumors of Cranial and Paraspinal Nerves | -- | -- | 6,630 | -- | -- | 6,380 |
| Nerve sheath tumors | -- | -- | -- | -- | -- | -- |
| Other tumors of cranial and paraspinal nerves | -- | -- | -- | -- | ||
| Tumors of Meninges | 460 | 36,760 | 37,210 | 440 | 37,620 | 38,060 |
| Meningiomas | 280 | 35,860 | 36,130 | 260 | 36,770 | 37,020 |
| Mesenchymal tumors | -- | -- | -- | -- | -- | -- |
| Primary melanocytic lesions | -- | -- | -- | -- | -- | -- |
| Lymphomas and Hematopoietic Neoplasms | 1,800 | -- | 1,800 | 1,830 | -- | 1,830 |
| Lymphoma | -- | -- | -- | -- | -- | -- |
| Other hematopoietic neoplasms | -- | -- | -- | -- | -- | -- |
| Germ Cell Tumors | -- | -- | 260 | -- | -- | 260 |
| Tumors of Sellar Region | -- | -- | 14,870 | -- | -- | 14,530 |
| Tumors of the pituitary | -- | -- | 14,230 | -- | -- | 13,870 |
| Craniopharyngioma | -- | -- | 650 | -- | -- | 650 |
| Unclassified Tumors | 1,340 | 2,070 | 3,410 | 1,340 | 1,960 | 3,300 |
| Hemangioma | -- | -- | 760 | -- | -- | 740 |
| Neoplasm, unspecified | 1,320 | 1,210 | 2,530 | 1,320 | 1,120 | 2,440 |
| All other | -- | -- | 120 | -- | -- | 120 |
| Total | 25,690 | 62,500 | 88,190 | 25,930 | 63,040 | 88,970 |
aSource: Estimation based on CBTRUS NPCR and SEER 2000–2018 data for malignant tumors, and NPCR and SEER 2006–2018 data for non-malignant tumors.
bRounded to the nearest 10. Numbers may not add up due to rounding.
cTotal estimate is based on overall estimate. Histology-specific estimates may not add up to total. -Estimated number is less than 50 or allows for back-calculation of a value less than 50. These cases are included in overall rates.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program