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. 2021 Oct 5;23(Suppl 3):iii1–iii105. doi: 10.1093/neuonc/noab200

Table 6.

Five-Year Total, Annual Average Totala, and Average Annual Age-Adjusted Incidence Ratesb with 95% Confidence Intervals for Selected Non-Malignant Histologies by Sex, Age Group at Diagnosis, Race, and Hispanic Ethnicity and Histology, CBTRUS Statistical Report: U.S. Cancer Statistics – NPCR and SEER, 2014–2018

Group Vestibular Schwannomac Pituitary Adenomad WHO Grade I Meningiomae WHO Grade II Meningiomaf
5-Year Total Annual Average 95% CI 5-Year Total Annual Average 95% CI 5-Year Total Annual Average 95% CI 5-Year Total Annual Average 95% CI
Sex
Male 12,874 2,575 1.49 (1.46–1.51) 28,821 5,764 3.41 (3.37–3.45) 13,080 2,616 1.52 (1.49–1.55) 3,913 783 0.46 (0.44–0.47)
Female 14,478 2,896 1.54 (1.51–1.57) 35,408 7,082 4.21 (4.17–4.26) 35,173 7,035 3.71 (3.67–3.75) 5,358 1,072 0.57 (0.56–0.59)
Age Groups
0–14 years 197 39 0.06 (0.06–0.07) 926 185 0.30 (0.28–0.32) 99 20 0.03 (0.03–0.04) 69 14 0.02 (0.02–0.03)
15–39 years 3,655 731 0.70 (0.68–0.73) 18,452 3,690 3.45 (3.40–3.50) 4,115 823 0.82 (0.80–0.85) 1,044 209 0.20 (0.19–0.21)
40–64 years 14,440 2,888 2.59 (2.54–2.63) 27,344 5,469 5.19 (5.12–5.25) 24,426 4,885 4.40 (4.34–4.46) 4,443 889 0.80 (0.78–0.82)
65+ years 9,060 1,812 3.65 (3.57–3.72) 17,507 3,501 7.18 (7.07–7.29) 19,613 3,923 8.05 (7.94–8.16) 3,715 743 1.54 (1.49–1.59)
Race
White 23,537 4,707 1.61 (1.58–1.63) 45,899 9,180 3.40 (3.37–3.43) 38,684 7,737 2.60 (2.58–2.63) 7,077 1,415 0.48 (0.47–0.49)
Black 1,496 299 0.69 (0.65–0.73) 12,835 2,567 6.04 (5.94–6.15) 6,223 1,245 2.96 (2.88–3.03) 1,452 290 0.69 (0.65–0.72)
American Indian/Alaska Native 159 32 0.77 (0.65–0.90) 541 108 2.61 (2.38–2.84) 313 63 1.65 (1.47–1.86) 52 10 0.28 (0.21–0.38)
Asian or Pacific Islander 1,525 305 1.46 (1.39–1.54) 3,583 717 3.45 (3.33–3.56) 2,402 480 2.36 (2.26–2.46) 548 110 0.54 (0.49–0.58)
Hispanic Ethnicity
Non-Hispanic 25,058 5,012 1.59 (1.57–1.62) 53,707 10,741 3.70 (3.67–3.73) 43,175 8,635 2.70 (2.68–2.73) 8,396 1,679 0.53 (0.52–0.54)
Hispanic 2,294 459 1.00 (0.96–1.05) 10,522 2,104 4.29 (4.20–4.38) 5,078 1,016 2.36 (2.29–2.43) 875 175 0.40 (0.38–0.43)
TOTAL 27,352 5,470 1.51 (1.49–1.53) 64,229 12,846 3.78 (3.75–3.81) 48,253 9,651 2.65 (2.63–2.68) 9,271 1,854 0.51 (0.50–0.52)

aAnnual average cases are calculated by dividing the five-year total by five.

bRates are per 100,000 and are age-adjusted to the 2000 US standard population.

cICD-O-3 histology code 9560/0 and ICD-O-3 topography code C72.4 and C72.5.

dICD-O-3 histology code 8272/0 and ICD-O-3 topography code C75.1.

eICD-O-3 histology codes 9530/0, 9531/0, 9532/0, 9533/0, 9534/0, and 9537/0.

fICD-O-3 histology codes 9530/1, 9531/1, 9532/1, 9533/1, 9534/1, 9537/1, 9538/1, and 9539/1.

-Counts and rates are not presented when fewer than 16 cases were reported for the specific category. The suppressed cases are included in the counts and rates for totals.

Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; CI, confidence interval