. 2021 Oct 3;11(10):e046966. doi: 10.1136/bmjopen-2020-046966

Table 1.

Basic characteristics of the included studies

Study	Year	Country	N	Setting	Operators	Quality score (Qi)	Reference standard	TP	FP	FN	TN	Se (%)	Sp (%)
Sharma et al²²	2012	UK	130	Home	Families	0.074	10g-MF	24	4	6	96	80.0	96.0
Sharma et al²³	2014	UK	331	Home	Families	0.714	10g-MF	65	15	18	233	78.3	93.9
Sharma et al²³	2014	UK	331	Clinic	Doctors/nurses	0.786	10g-MF	67	9	16	239	81.2	96.4
Amal Madanat et al²⁴	2015	Saudi Arabia	351	Care centres	Doctors/nurses	0.357	10g-MF	29	6	28	288	51.0	98.0
							VPT	48	24	9	270	85	92
							NDS	30	9	27	285	53	97
Basir et al²⁵	2020	Spain	100	Care centres	Doctors/nurses	0.429	10g-MF	4	30	1	65	80.0	68.0
							Pin prick	4	1	11	84	80.0	88.0
							Tuning fork 128 Hz	2	3	69	26	40.0	27.0
							Ankle reflex	1	4	2	93	20.0	97.0
Dutra et al²⁶	2020	Brasília	250	Outpatient centre	Doctors/nurses	0.643	10g-MF	30	5	6	209	83.3	97.7
Rayman et al¹⁹	2011	UK	265	Clinic	–	–	VPT	–	–	–	–	76.0	90.0
Bowling et al²⁷	2012	UK	83	Clinic	Doctors/nurses	–	VPT	–	–	–	–	100	96.6
Bowling et al²⁷	2012	UK	83	Clinic	Doctors/nurses	–	NDS	–	–	–	–	100	90.3

FN, false negative number; FP, false positive number; 10g-MF, 10 g monofilament; NDS, neuropathy disability scores; SE, sensitivity; Sp, specificity; TN, true negative number; TP, true positive number; VPT, vibration perception threshold.