Table 2.
Oxidative stress and antioxidant enzyme activity in asymptomatic (reticular) and symptomatic (erosive) oral lichen planus lesions compared to samples from control subjects
| Oxidative stress marker | Mean±SD | ||
|---|---|---|---|
|
| |||
| Control | OLP-R | OLP-E | |
| Reduced GSH (µmol/mg of tissue) | 5.78±1.4 | 2.69±0.8 | 0.81±0.68 |
| GR (nmol NADPH oxidised/min/mg protein) | 8.81±1.02 | 3.66±1.03 | 1.94±0.61 |
| GPX (nmol NADPH oxidized/min/mg protein) | 4.27±1.11 | 2.25±0.80 | 0.50±0.15 |
| GST (nmol/min/mg of protein) | 9.58±2.11 | 5.32±1.05 | 2.38±1.04 |
| SOD (Unit/mg protein) | 0.44±0.24 | 1.07±0.36 | 2.25±0.68 |
| CAT (µmol/min/mg of protein) | 35.74±5.42 | 60.26±7.55 | 76.06±10 |
| Lipid peroxidation (MDA) (nmol/mg protein) | 1.12±0.36 | 3.07±0.68 | 6.35±1.72 |
| Nitrite level (nmol/mg of tissue) | 410±52.34 | 524.2.4±49.1 | 666.4±34.76 |
OLP-R: Oral lichen planus-reticular, OLP-E: Oral lichen planus-erosive, GR: Glutathione reductase, GPX: Glutathione peroxidase, GST: Glutathione-s-transferase, SOD: Superoxide dismutase, CAT: Catalase, GSH: Glutathione, MDA: Malondialdehyde, SD: Standard deviation, NADPH: Nicotinamide adenine dinucleotide phosphate