Table 2.
Unadjusted and adjusted annual change in demographic and cardiovascular risk factors in patients enrolled in Tehran Heart Center Databank from 2005 to 2015
| Unadjusted annual change (95% CI)a | P-value | Adjusted annual change (95% CI)b | P-value | |
|---|---|---|---|---|
| Age at diagnosis (n = 90,094, years) | 0.12 (0.10, 0.15) | < 0.001 | 0.12 (0.10, 0.14) | < 0.001 |
| Sex (n = 90,094, % male) | − 0.11 (− 0.21, − 0.01) | 0.03 | − 0.04 (− 0.14, 0.06) | 0.43 |
| Body mass index (n = 65,320, kg/m2) | 0.08 (0.07, 0.10) | < 0.001 | 0.09 (0.08, 0.10) | < 0.001 |
| Total Cholesterol (n = 81,363, mg/dL) | − 3.27 (− 3.38, − 3.17) | < 0.001 | − 3.23 (− 3.33, − 3.13) | < 0.001 |
| LDL Cholesterol (n = 79,458, mg/dL) | − 1.48 (− 1.56, − 1.39) | < 0.001 | − 1.45 (− 1.54, − 1.37) | < 0.001 |
| HDL Cholesterol (n = 80,899, mg/dL) | − 0.41 (− 0.44, − 0.39) | < 0.001 | − 0.42 (− 0.44, − 0.40) | < 0.001 |
| Triglycerides (n = 81,390, mg/dL) | − 4.51 (− 4.73, − 4.29) | < 0.001 | − 4.35 (− 4.57, − 4.14) | < 0.001 |
| Dyslipidemia (n = 89,899, % yes) | − 0.20 (− 0.31, − 0.10) | < 0.001 | − 0.17 (− 0.27, − 0.07) | 0.001 |
| Fasting blood sugar (n = 79,822, mg/dL) | − 0.03 (− 0.15, 0.09) | 0.65 | − 0.02 (− 0.14, 0.10) | 0.77 |
| Diabetes mellitus (n = 89,977, % yes) | 0.62 (0.51, 0.72) | < 0.001 | 0.58 (0.48, 0.68) | < 0.001 |
| Hypertension (n = 90,001, % yes) | 1.16 (1.06, 1.27) | < 0.001 | 1.05 (0.95, 1.15) | < 0.001 |
| Ever cigarette smoking (n = 89,955, % yes) | − 0.29 (− 0.39, − 0.19) | < 0.001 | − 0.16 (− 0.25, − 0.07) | 0.001 |
| Ever opium use (n = 87,348, % yes) | 0.15 (0.08, 0.23) | < 0.001 | 0.23 (0.15, 0.30) | < 0.001 |
aAll changes are annual. Changes for categorical variables (sex, dyslipidemia, diabetes, hypertension, ever cigarette smoking, and ever opium use) are percentages per year. Changes for continuous variables (age; body mass index; total, LDL, HDL cholesterol; triglycerides; fasting blood sugar) are using the unit shown in the first column
bAdjusted for age and sex