Table 5.

Association of GRIN family genotypes with plasma CaMK2A levels and cognitive ability

		N	Mean	SD	F	P
GRIN3A_rs3739722
CaMK2A Conc	CC	70	401.98	240.01	3.041	> 0.05
	CT	43	424.45	224.42
	TT	7	190.62	223.68
Cognitive ability	CC	70	45.76	42.57	4.891	0.009*
	CT	43	56.40	40.61
	TT	7	5	2.45
GRIN3B_ rs2240154
CaMK2A Conc	CC	44	427.66	258.17	0.686	> 0.05
	CT	56	371.80	222.85
	TT	20	404.31	234.75
Cognitive ability	CC	44	61.68	40.35	5.219	0.007*
	CT	56	42.34	41.88
	TT	2	28.90	37.58
GRIN3B_rs4807399
CaMK2A Conc	CC	98	374.67	239.60	4.299	0.016*
	CT	20	528.64	184.27
	TT	2	216.90	220.70
Cognitive ability	CC	98	42.75	41.58	3.377	0.037*
	CT	20	69.05	37.89
	TT	2	46.50	64.35
GRIN3B_2240157
CaMK2A Conc	CC	42	429.98	262.68	0.679	> 0.05
	CT	55	373.07	221.50
	TT	23	397.67	230.31
Cognitive ability	CC	42	62.29	40.31	5.35	0.006*
	CT	55	43.02	41.93
	TT	23	29.61	37.79
GRIN3B_rs2285906
CaMK2A Conc	AA	3	342.32	278.78	1.081	> 0.05
	AG	41	441.34	240.59
	GG	76	376.35	234.66
Cognitive ability	AA	3	35.33	49.23	4.032	0.020*
	AG	41	61.93	39.58
	GG	76	39.71	41.55
GRIN3B_rs10417824
CaMK2A Conc	AA	18	457.39	270.92	4.686	0.011*
	AT	60	441.06	220.98
	TT	42	310.19	226.06
Cognitive ability	AA	18	70.94	35.94	8.571	0.000*
	AT	60	53.13	42.42
	TT	42	28.52	36.80
GRIN3B_rs10401454
CaMK2A Conc	CC	75	371.39	223.99	1.489	> 0.05
	CG	35	454.98	259.31
	GG	10	394.64	248.75
Cognitive ability	CC	75	39.09	41.74	4.391	0.014*
	CG	35	57.51	40.78
	GG	10	71.80	34.07

^*p value < 0.05