Table 1.
Summary of the clinical features of the enrolled cases (N=67)
| Parameters | *MSI-high (N=20) (%) | POLE-mutated (N=47) (%) | Total (%) | |
| Age (mean±SD) | 48.8±11.9 | 61.4±11.7 | 57.7±13.1 | |
| Sex | Male | 14 (70) | 30 (64) | 44 (66) |
| Female | 6 (30) | 17 (36) | 23 (34) | |
| Type of malignancies | CRC | 14 (70) | 25 (53) | 39 (58) |
| NSCLC | 0 | 12 (26) | 12 (18) | |
| GC | 3 (15) | 6 (13) | 9 (13.5) | |
| GBM | 2 (10) | 0 | 2 (3) | |
| OV | 1 (5) | 1 (2) | 2 (3) | |
| BC | 0 | 1 (2) | 1 (1.5) | |
| SCLC | 0 | 1 (2) | 1 (1.5) | |
| HNSCC | 0 | 1 (2) | 1 (1.5) | |
*Defined by the published criteria of Kim et al.19
BC, breast cancer; CRC, colorectal cancer; GBM, glioblastoma; GC, gastric cancer; HNSCC, head and neck squamous cell carcinoma; MSI, microsatellite instability; NSCLC, non-small cell carcinoma; OV, ovarian cancer; SCLC, small cell lung carcinoma.