Skip to main content
. 2021 Oct 3;9(10):e003499. doi: 10.1136/jitc-2021-003499

Table 1.

Baseline patient characteristics

ID Diagnosis Histology details Age Sex Years with cancer Previous lines of therapy
1 Colon cancer Mucusal AC, KRASmut 65 F 6.3 2
2 Colon cancer AC, KRASmut, MSI-low, 63 M 2.9 3
3 Colon cancer AC, KRASmut, MSI-low 55 F 5.1 2
4 Colon cancer AC, MSS 57 F 12.3 4
5 Colon cancer AC, BRAFmut 44 M 1.2 2
6 Rectal cancer AC, KRASmut, MSS 53 F 3.3 2
7 Rectal cancer AC, MSS 45 M 2.4 4
8 CC Chronic inflammation 66 F 3.9 2
9 CC FGFR fusion 54 F 13.1 10*
10 CC Klatskin 50 M 3 2*
11 Melanoma (skin) PD-L1neg, BRAFwt 46 M 2.9 1†
12 Melanoma (skin) PD-L1neg, BRAFmut 51 F 8.4 3†
13 Melanoma (choridea) BRAFwt 47 F 4.9 2*
14 Melanoma (choridea) BRAFwt 39 M 12.9 4*
15 Melanoma (choridea) 63 F 3.9 1*
16 Melanoma (choridea) BRAFwt 55 M 1.2 2†
17 Leiomyosarcoma Uterus-derived 48 F 2.9 3
18 Leiomyosarcoma Liver-derived, grade 3 51 M 5.1 1
19 Oropharyngeal cancer (HNSCC) SCC, P16+ 57 M 5.3 2*
20 Cervix cancer SCC, P16+, P40+ 40 F 9.5 5*
21 Myoepithelial carcinoma PD-L1neg 65 M 2.7 1
22 Adrenocorticocarcinoma Weiss score 9 64 F 0.9 1
23 Non-small cell lung cancer AC, PD-L1neg 45 F 6 4
24 Rhinopharyngeal cancer Low diff. 43 F 4.5 2
25 Thyroid cancer Low diff. 57 M 4.3 3
Median/ratio 53 11:14 4.3 2

Overview of all patients treated with adoptive cell therapy in the clinical trial.

*Included anti-PD-1/PD-L1.

†Included anti-PD-1 and anti-CTLA-4.

AC, adenocarcinoma; CC, cholangiocarcinoma; F, female; FGFR, fibroblast growth factor receptor; HNSCC, head-and-neck squamous cell carcinoma; M, male; MSI, microsatelite instability; MSS, microsatelite stability; SCC, squamous cell carcinoma.