PCA of protein levels in lesional (n = 64 samples), peri-lesional (n = 64 samples), and non-lesional skin (n = 32 samples). Biplot of dimension 1 (horizontal axis) and 2 (vertical axis). Each dot represents one sample. Levels of 11 proteins were included: CXCL-1/2, CCL-27, IL-1RA, IL-23, IL-1α, IL-8, IL-22, VEGF, hBD-2, hBD-1, and KLK-5. CXCL, CXC chemokine ligand; CCL, CC chemokine ligand; IL, interleukin; VEGF, vascular endothelial growth factor; hBD, human beta-defensin; KLK, kallikrein-related peptidase; PCA, principal component analysis.