Fig. 4.

Absolute counts of proteins in the lesional skin (n = 64 samples) measured by TAP split for patients on solely topical treatment (n = 38 samples) versus systemic treatment (n = 26 samples). Each dot represents 1 measurement. The Mann-Whitney U test was used to assess differences between measurements of patients on solely topical versus systemic treatment. L, lesional; PL, peri-lesional; NL, non-lesional; *p < 0.05, **p < 0.01, ***p < 0.001; ns, nonsignificant. CCL, CC chemokine ligand; IL, interleukin; hBD, human beta-defensin; KLK, kallikrein-related peptidase; TAP, transdermal analysis patch.