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IC50 values of micelles (n = 6).
|
|
IC50 [μM] |
||||
|---|---|---|---|---|---|
| Micelle | Bl6F 10 | P1C3 | 22Rvl | NCI-H460 | RWPE-1 |
|
| |||||
| KLAK-MCP-1 | 1.4 ± 0.3a,b | 18.0 ± 1.4 | 31.3 ± 11.0 | >50 | >50 |
| KLAK-scr-MCP1 | 17.8 ± 2.2 | >50 | >50 | >50 | >50 |
| KLAK | 7.0 ± 2.7 | >50 | >50 | >50 | >50 |
| MCP-1 | 31.9 ± 7.0 | 47.5 ± 12.4 | >50 | >50 | >50 |
| Scr-MCP-1 | >50 | >50 | >50 | >50 | >50 |
| Empty | >50 | >50 | >50 | >50 | >50 |
p < 0.005 compared to KLAK-MCP-1 IC50 in PC3 and 22Rvl.
p < 0.0001 compared to KLAK-scr-MCP-1 and MCP-1 in Bl6Fl0.
