Figure 2 .

Superagers exhibit more youthful neural differentiation during encoding of distinct categories of visual information. (A) During the encoding of face–word pairs and scene–word pairs, superagers exhibited neural differentiation similar to that of young adults, while typical older adults showed reduced neural differentiation (^*TOA is different from YA and SA at P < 0.05). Neural differentiation is a measure that represents how distinct regional brain activation patterns are when viewing items that are from the same category relative to when viewing items that are from different categories (see Fig. 1 for more details on this measure). (B) The effect shown in (A) was driven primarily by group differences in within-category RS (i.e., comparing face–face or scene–scene trial pairs; shown in dark blue bars). (C) Group average RS matrices illustrate the effects quantified in (A) and (B). YA, young adults; SA, superagers; TOA, typical older adults. Error bars denote one standard error of the mean.