Table 1.
Characteristics of the two study cohorts (ADNI and DELCODE)
| DELCODE | ADNI | |||||
|---|---|---|---|---|---|---|
| AD (N = 103) | HC (N = 63) | AD (N = 121) | HC (N = 30) | P between AD groups | P between HC groups | |
| Age, mean (SD) | 74 (6) | 69 (5) | 75 (8) | 77 (8) | 0.33a | <0.001a |
| Sex, no. female %, (SD) | 57 (55) | 32 (49) | 63 (52) | 21 (70) | 0.72b | <0.001b |
| Years of education, mean (SD) | 14 (3) | 14 (3) | 16 (2) | 16 (3) | <0.001a | 0.07a |
| MMSE, mean (SD) | 26 (3) | 29 (1) | 25 (4) | 29 (1)d | 0.36a | 0.06a |
| CDR-SoB, mean (SD) | 2.7 (2.2) | 0 | 3.2 (2.6) | 0 | 0.06a | 1a |
| APOE, no. (%) ε4 allele carrier (SD) | 66 (64)d | 9 (14) | 68 (56)c | 6 (21) | 0.39b | 0.64b |
Abbreviation: APOE, apolipoprotein ε4 genotype.
aKruskal–Wallis test.
bChi-squared-test.
cMissing data for n = 4 participants.
dMissing data for n = 1 participant.