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. 2021 Sep 30;59(1):1349–1356. doi: 10.1080/13880209.2021.1981399

Figure 4.

Figure 4.

Pristimerin ameliorates neuronal cell apoptosis in brain tissue homogenates of mice with sepsis-induced brain injuries. (A) Effects of pristimerin on expression levels of Bax, Bcl-2 and caspase-3, as revealed by Western blotting. (B) Effect of pristimerin on the apoptosis index, as revealed by the TUNEL assay. TUNEL: terminal deoxynucleotidyl transferase dUTP nick end-labelling. Means ± SEMs (n = 10); ##p < 0.01 compared with positive controls; **p < 0.01 compared with negative controls.