Synonymous and non-synonymous codon changes in ACMV and EACMCV. Diagram of the locations of synonymous codon changes (grey), unassigned changes in overlapping open reading frames (ORFs; green), and non-synonymous changes for (a) ACMV (blue) and (b) EACMCV (red). The number of synonymous (c) and non-synonymous (d) codon changes normalized to the total number of codons in the ORF for ACMV (dark grey and blue) and EACMCV (light grey and red). The number if synonymous (grey) and non-synonymous (ACMV-blue, EACMCV-red) codon changes in overlapping coding sequences in ORFs overlapping within ACMV excluding AC5 (e), EACMCV (f), and regions within ACMV that overlap AC5 (g). The overlapping ORF is designated first and the ORF assessed for the codon change is designated second in bold.