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. 2021 Sep 20;17(9):e1009733. doi: 10.1371/journal.pgen.1009733

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© 2021 LaPierre et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Simulated Z-scores for SNPs at a quantitative trait locus in two different populations: East Asians (top) and Europeans (bottom), shown by their −log₁₀(p-value). LD matrices for these populations were derived using data from the 1000 Genomes project. These are the input files to MsCAVIAR. (B) Meta-analysis results for this locus, showing many significant SNPs. Also displayed are the SNPs that are in the causal set that MsCAVIAR returns (red stars) and the truly causal SNPs (black stars).